Early stages of lid gland dysfunction can present with abnormalities in the lipid structure of the lid gland, leading to increased viscosity of secretions and consequent blockage of the ducts, an environment that is conducive to bacterial colonization and leads to lid gland dysfunction. In addition, ocular inflammation, external factors, and systemic diseases can be risk factors for lid gland dysfunction for the following reasons: 1) ocular inflammation: e.g., blepharitis, dry eye, ocular mite infection; 2) external factors: e.g., corneal contact lens contamination, overly dry environment, air pollution; 3) other risk factors: hormonal changes in the body, e.g., estrogen replacement therapy in perimenopausal women Lupus erythematosus, rosacea, and metabolic diseases such as diabetes can be risk factors for blepharoplasty dysfunction.