Mid-pregnancy pain in the abdomen, there are several possible reasons: first, caused by preeclampsia, the pain is usually accompanied by vaginal bleeding. Second, some other diseases, such as acute gastroenteritis, proctitis, as well as some diseases of the urinary system, such as urinary stones, urinary tract infections. Third, gynecological diseases, such as adnexitis. Fourth, some inflammatory lesions in the abdomen, such as appendicitis, cholecystitis and other causes. If the abdomen in mid-pregnancy has been painful, it is recommended to go to a regular specialized hospital for a systematic and complete examination and a clear diagnosis.