Squatting up knee pain generally has the following causes: first, patellofemoral arthritis, patellofemoral joint exists between the patella and femur of the knee joint, when it has chronic inflammation, there can be damage to the cartilage, when squatting up there can be pain in front of the knee, this time to carry out the relevant knee X-ray, nuclear magnetic examination for diagnosis, after diagnosis can be oral nutritional cartilage drug therapy or joint After diagnosis, oral cartilage-nourishing drugs or intra-articular injection of sodium vitreous acid can be used. Second, meniscal injury, when there is damage to the posterior horn of the meniscus, there can be pain in the knee joint when squatting, because the posterior horn of the meniscus is squeezed when squatting, there can be pain when getting up. Third, osteoarthritis, when there is osteoarthritis, there can also be pain in the knee after squatting, then the knee X-ray, CT, MRI for diagnosis and treatment.