Since the 21st century, with the continuous improvement of medical technology and the rapid development of modern medical equipment, interventional techniques are playing an increasingly important role in the treatment of malignant tumors. Due to no need for incision, little damage and fast recovery, this therapy is now one of the main treatment methods for many cancers (e.g. liver cancer, lung cancer, etc.), and even replaces or eliminates the original surgical procedures. Interventional tumor treatment is the application of puncture and cannulation techniques, and the catheter is precisely and selectively inserted into the blood supplying target artery related to the tumor lesion under the guidance of a large X-ray television fluoroscopy machine, through which highly concentrated chemotherapeutic drugs are precisely and directly infused into the lesion, with strong killing power and high efficacy. After the infusion, the tumor blood vessel bed is blocked with embolic agent to cut off the nutrition supply of tumor and “starve” the tumor cells. Since this technology does not require incision to expose the lesion, it can reduce the patient’s pain and protect the integrity of normal tissues and organs around the tumor to the greatest extent, and has been widely used in clinical practice with its characteristics of minimally invasive, quick effect and repeatability. At present, tumor interventional therapy, such as interventional embolization, microwave, radio frequency, freezing, laser, injection of anhydrous ethanol and other physicochemical ablation methods have solved many tumor treatment problems, especially for patients with advanced stage or traditional surgery failure. For certain early small solid tumors such as small hepatocellular carcinoma, the use of minimally invasive ablation therapy can achieve the same effect as surgical liver resection. Although there are many advantages of tumor interventional therapy, its limitations cannot be avoided, which are mainly three: 1. Even if the operation is successfully selected, it can lead to misembolization, shunt and possible inevitable micrometastasis due to high pressure injection, which can cause serious consequences. It is worth mentioning that at present, interventional treatment is generally used as palliative treatment only, and even if it is completed, it is only a small step in the “long march” of cancer treatment, which is still far from real recovery. Therefore, experts suggest that interventional treatment can be combined with targeted drug therapy, which can not only expand the efficacy of interventional treatment, but also reduce the side effects to the human body, giving full play to the synergistic effect and achieving the effect of 1+1〉2.