Taking hormones will not cause mitral tricuspid regurgitation. Hormones include a variety of hormones, such as glucocorticoids, sex hormones, etc. Hormones will affect the body’s metabolism, such as the emergence of abnormal glucose metabolism, abnormal lipid metabolism, etc., but will not have a direct impact on the heart valve, and rarely will there be regurgitation of the heart valve. There are many reasons for heart valve regurgitation, common reasons include aging of the valve, mostly seen in elderly patients, some patients may have rheumatic heart disease, rheumatic inflammation can lead to valve closure insufficiency regurgitation. Taking hormones alone will not affect the function of the heart valves, but if it is combined with other diseases at the same time, such as rheumatic diseases, there is a possibility that the heart valves will become diseased and regurgitation will occur in the valve area. Hormones should be used under the guidance of a doctor and not on their own.