Drinking a lot of water whether the urine protein can become negative, to be analyzed on a case-by-case basis. If the physiological proteinuria, after drinking a lot of water may appear urine protein negative, but for pathological proteinuria, will not turn negative. 1. Negative: some patients if there is exertion, after strenuous exercise, there may be positive urine protein, at this time, mostly transient, drink more water, more urination, pay attention to rest, remove the causative factors, the general urine protein can become negative. 2. Can not be transformed: but some patients are due to pathological factors that lead to urinary protein such as glomerulonephritis, nephrotic syndrome, hypertensive nephropathy, etc., these appearances of urinary protein generally will not turn negative. Examination found proteinuria, should actively consult the doctor, clear cause and symptomatic treatment, do not private treatment, so as not to delay the condition.