Wake up at 4~5 o’clock in the morning is known as the phenomenon of early waking up in the medical field, which can be divided into physiological and pathological reasons, pathological reasons are psychological diseases and cardiovascular diseases. 1. Physiological: some people sleep earlier, such as nine or ten o’clock in the night has gone to sleep, then 4 ~ 5 o’clock in the morning to wake up more than belong to the normal physiological phenomenon, without additional special treatment. 2. Pathological: psychological disorders are the most common cause of this phenomenon, such as anxiety, depression and sleep disorders, which can lead to mental tension or excitement, thus resulting in this symptom; and cardiovascular diseases, such as hypertension, hypertension will be due to the rise in blood pressure in the morning leading to discomfort and thus the phenomenon of waking up early. If you suspect that this symptom is pathological, it is recommended that you seek medical treatment promptly.