The patient was admitted to the hospital with “brain contusion, lower extremity fracture and multiple rib fractures for 24 hours due to car accident injury”. Suggestions: bilateral pulmonary artery trunk embolism (90%), upper sagittal sinus sigmoid sinus thrombosis, lower extremity ultrasound suggested right N vein superficial femoral vein thrombosis, left lower extremity undetected vein thrombosis. The right femoral vein was not found to be thrombosed and no inferior vena cava thrombosis was found. The guidewire catheter was passed up into the pulmonary artery, and the image showed bilateral pulmonary artery embolism and a small area of right and left superior pulmonary artery. The pulmonary artery catheter was pushed with 200,000 units of urokinase (100,000 units in each of the right and left pulmonary arteries). 5 minutes later, the re-imaging showed that the entire pulmonary artery trunk was visualized, the secondary and tertiary branches of both pulmonary arteries were more than 50% visualized, and the oxygen saturation reached 80% in the case of 50% FiO2, the pulmonary artery catheter was withdrawn, and the superior vena cava was upgraded, and no thrombus was found in the left and right unnamed veins of the internal jugular vein. A permanent inferior vena cava filter was placed in the second lumbar plane. The patient was hemodynamically stable in 75 minutes and was returned to the SICU.