Patients with hepatitis B can, through study, have interferon injections at home if they master asepsis. Interferon injections are mainly subcutaneous and require sterilization of the skin of the left or right upper arm prior to the injection, which is done through a 1mL syringe after sterilizing the skin. Adverse reactions such as headache, fever, chills and myalgia may occur during the injection of the drug. The drug is contraindicated in patients who are allergic to the components of the drug, and it should be used with caution in patients with pre-existing heart disease. The drug should be used under the guidance of a doctor and avoid unauthorized use of the drug to avoid adverse effects. In addition, during the injection of interferon, regular follow-up of blood routine, liver function, thyroid function and so on is needed. If serious discomfort occurs during interferon injection, it is recommended to consult a doctor in time to improve the relevant examination, clarify the cause of the disease and treat the symptoms.