1, the vaccine is the first choice for the prevention of hepatitis B. The country has implemented a control strategy based on preventive vaccination of newborns against hepatitis B Vaccination against hepatitis B is the safest and most effective measure to prevent hepatitis B. After the whole course of hepatitis B vaccination, about 80%-95% of the population can develop immunity, and the protective effect can last for more than 20 years. Since hepatitis B virus infection is the main factor leading to primary liver cancer, hepatitis B vaccination can also reduce the incidence of primary liver cancer. Hepatitis B virus infection can only occur simultaneously with or on top of hepatitis B virus infection, so hepatitis B vaccination can also prevent hepatitis D virus infection. In 1992, the strategy of hepatitis B vaccination for newborns was introduced, and since 2002, China has implemented the strategy of free hepatitis B vaccination for newborns, and the first dose should be given within 24 hours of birth, and the whole vaccination process should be completed. To protect children and adolescents from the risk of hepatitis B virus. Medical personnel, people who have frequent contact with blood, workers in childcare institutions, frequent recipients of blood transfusions or blood products, family members of people with positive surface antigen for hepatitis B virus, men who have sex with men or multiple sexual partners, and people who inject drugs intravenously should also receive hepatitis B vaccination. Hepatitis A and E viruses are mainly transmitted through the gastrointestinal tract, so paying attention to dietary and drinking water hygiene and preventing “illness from the mouth” can prevent hepatitis A and E virus infection. Hepatitis A vaccine has been incorporated into the national immunization program, and children aged 18 months are given free vaccination against hepatitis A. One dose of live attenuated hepatitis A vaccine is given, and two doses of inactivated vaccine are given at six-month intervals. Vaccination against hepatitis A can effectively prevent hepatitis A. 3. Cut off the transmission route to prevent hepatitis C Although hepatitis C cannot be prevented by vaccination at present, it can be completely prevented by taking effective measures to cut off its transmission route (such as using safe blood products, not sharing syringes, avoiding unclean medical practices, etc.).