The last two positives of Hepatitis B Penta indicate previous infection with Hepatitis B virus or recovery from acute Hepatitis B infection. The last two positives of Hepatitis B 5 are positive for Hepatitis B e-antibody and core antibody. e-antibody positivity indicates that the level of Hepatitis B virus DNA replication has decreased, but it is still contagious. Positive core antibody indicates that you have been infected with hepatitis B virus. And these two positive at the same time suggests that the previous infection of hepatitis B virus or acute hepatitis B infection recovery period. At this time, although the hepatitis B surface antigen is negative, there may still be replication of hepatitis B virus DNA, and a few specimens are still infectious, and if the hepatitis B virus DNA test can also be positive, liver damage may also exist at the same time. Therefore, it is recommended that the patient should consult the doctor in time, complete the relevant examinations under the guidance of the doctor, and timely treatment when needed.