Clinical neck and shoulder, lumbar and leg pain are common clinical symptoms, accounting for about 4/5 of the number of outpatient spine surgery cases. Cervical and lumbar disc herniation is the main cause of these symptoms, and the treatment of cervical and lumbar disc herniation has undergone nearly 80 years of progress and is still being explored. The last decade has been a decade of rapid development in spinal surgery technology, and the treatment of cervical and lumbar disc herniation has gained breakthroughs and treatment methods have been enriched. Traditional methods such as traction, physical therapy, drugs, closure, and surgery still dominate, and the development of minimally invasive technology provides more aggressive treatment options for patients whose conservative treatment is ineffective. Since 2003, there have been about 1800 domestic and foreign reports on the use of minimally invasive techniques for the treatment of cervical and lumbar disc herniation, nearly half of which involve minimally invasive nucleus pulposus ablation and nucleus pulposus formation, and these two techniques have been carried out domestically and internationally. The personnel engaged in these techniques mainly include physicians in spine surgery, pain medicine, rehabilitation, reflexology intervention, and traditional Chinese medicine, etc. Each specialty has a good understanding of the principles of cervical and lumbar disc herniation treatment, the Although the process is minimally invasive, the criteria for judging the efficacy are the same as those for traditional surgery (or endoscopic surgery), and only with such rigor can we expect to maintain good long-term efficacy and ensure the longevity of this technology. The only way to maintain good long-term results and ensure the longevity of this technology is to be so strict. At present, there are many minimally invasive myeloablative and myeloforming techniques in clinical use, including laser, plasma, radiofrequency thermocoagulation, etc. All these methods use specific temperature to consolidate the nucleus pulposus and reduce the intradiscal pressure to achieve the purpose of indirect decompression, which belongs to the category of myeloforming; collagenase and ozone use special chemical components to dissolve the nucleus pulposus and achieve the purpose of intradiscal pressure reduction, which belongs to the category of myeloablation. The ultimate goal of the above methods is to achieve indirect nerve root decompression through intradiscal decompression, which is more effective in cases with intact annulus fibrosus, but not in cases with ruptured annulus fibrosus, and has limited indications. With reference to the surgical principle of intervertebral disc herniation, the target radiofrequency carried out in recent years has for the first time put the puncture needle into the herniated disc and put forward the concept of direct decompression by radiofrequency or plasma, but its action area on the nucleus pulposus is more limited; ozone ablation has more precise efficacy and better safety than collagenase, and its intra-disc action range is wider, which can better compensate for the limitation of target radiofrequency, and the combined application of the two has a broad prospect. The combination of RF and ozone ablation is a non-invasive minimally invasive technique with the following advantages: 1) its unique safety alarm system and the surgical method without anesthesia (or local anesthesia) solve the disadvantages of the general minimally invasive spinal techniques that increase the risk of nerve injury; 2) the direct access to the herniated nucleus pulposus (target point) through the intervertebral space can achieve direct decompression and reduce the inflammatory response, which solves the problem of the previous collateral approach 3. The combination of radiofrequency and ozone ablation at the disc target point not only considers the problem of direct decompression, but also uses ozone ablation to resolve the residual nucleus pulposus, which is close to the principle of endoscopic nucleus pulposus removal and is expected to achieve better long-term results. The development of minimally invasive disc target radiofrequency combined with ozone ablation technology will greatly reduce the average hospital stay and increase the annual surgical volume by 20-30%; the academic value to the department and hospital is more worthy of expectation, which will enable spine surgery to grasp the development trend of minimally invasive spine, and gradually form the core technology of the department together with spinal endoscopic technology, driving the development of the whole discipline.