A woman’s inexplicable irritability may be clinically considered to be a neurological disorder or a menstrual depressive disorder. The first thing to determine is the relationship between the inexplicable irritability and the menstrual cycle. If this irritability or irritability is closely related to menstruation, it should be observed. Before menstruation, women often experience irritability, irritability, conflicts with others, decreased work efficiency, and a series of psychosomatic symptoms related to menstruation, such as mental tension and sometimes breast tenderness. If the symptoms appear before menstruation and are most serious 2-3 days before menstruation and suddenly disappear after menstruation, it may be a possibility of menstrual depression. In addition, if a woman is often inexplicably irritable and has physical symptoms such as dizziness, headache, panic, shortness of breath, sweating, worry and fear, fidgeting and other related symptoms, it needs to be considered as a possible anxiety and anxiety-related disorder. Once diagnosed with anxiety disorder related disorders, anti-anxiety medication and psychotherapy are required, and generally good treatment results can be achieved.