Clinically, chronic kidney disease can be classified into 5 stages based on the value of glomerular filtration rate. The glomerular filtration rate of patients with stage 4 chronic kidney disease ranges from 15-29 ml/min, while the glomerular filtration rate of patients with stage 5 is less than 15 ml/min. The time required to develop stage 4 kidney disease to stage 5 is mainly related to the presence or absence of other underlying diseases and the current renal pathology of patients, and there are individual differences and the rate of progression varies, from a few weeks to 2-3 years . For patients with underlying diseases such as hypertension and diabetes, or chronic glomerulonephritis with more proteinuria, the disease progresses more rapidly. When patients show symptoms related to uremia, such as heart failure, gastrointestinal bleeding, mental abnormalities and other manifestations, it mostly indicates that they have progressed to stage 5 and need to be given dialysis treatment, which may be life-threatening in severe cases. In conclusion, regardless of the stage, patients with kidney disease need to be given a low salt and low protein diet, and to control the intake of potassium and phosphorus, and the staple food can be replaced by potatoes instead of rice and noodles, etc.