Melasma is a pigment increasing disease, which is usually treated with symptomatic and comprehensive treatment. Patients need to follow medical advice to reasonably choose drugs, laser and other treatments, and the common treatment methods are mainly as follows: 1. Topical medication: hydroquinone cream is the first-line medication for melasma, which can stop tyrosine synthesis and play the role of color fading. Azelaic acid cream, vitamin A acid, tretinoin cream and ursolic acid cream also have the effect of lightening melasma, in addition, fruit acids can also be used for supplementary treatment; 2. Systemic medication: oral medications, such as tranexamic acid tablets, vitamin C, vitamin E and herbal tonics can be used for systematic treatment. The combination of vitamin C and vitamin E has the effect of anti-lipid peroxidation and inhibition of melanin synthesis. In case of serious disease, tranexamic acid, vitamin C, reduced glutathione and other drugs can be injected intravenously; 3. Photoelectric treatment: chloasma can be treated by picosecond, super picosecond laser and intense pulsed light; 4. Treatment of primary disease: if the patient has hypothyroidism, liver disease or gynecological disease, the primary disease needs to be treated simultaneously; 5. Other: prevention of ultraviolet radiation is the basis of treatment of chloasma, and the patient needs to pay attention to daily Sun protection, moisturizing and hydration to reduce the influence of sunlight.