Methods of removing melanin from the skin surface mainly include medication, physical therapy and auxiliary therapy. 1. Medication: Topical depigmenting agents such as tretinoin, azelaic acid cream and compound arbutin cream can inhibit the activity of tyrosinase and reduce the production of melanin. Topical retinoic acid ointment can also affect melanin metabolism, which has a certain improvement effect on hyperpigmentation. If necessary, oral vitamin C, vitamin E, etc. can also be used to reduce melanin deposition. 2. Physical therapy and auxiliary treatment: photorejuvenation, Q laser, intense pulsed light, etc. can be broken by high energy melanin particles to reduce melanin deposition; fruit acid, salicylic acid and other chemical peeling to improve the skin melanin deposition also has a certain effect. It is recommended that patients go to the dermatology department of regular hospitals for consultation and standardized treatment under the guidance of doctors, and do not blindly self-medication.