The main pathological change in hypertrophic cardiomyopathy is asymmetric progressive myocardial hypertrophy. Depending on the location and degree of myocardial hypertrophy, there are two types: 1. Hypertrophic obstructive cardiomyopathy is called hypertrophic obstructive cardiomyopathy if septal hypertrophy is the main cause of outflow tract obstruction; 2. Hypertrophic non-obstructive cardiomyopathy is called hypertrophic non-obstructive cardiomyopathy if there is no outflow tract obstruction. The main clinical manifestations are dyspnea, angina pectoris, syncope, palpitations, weakness, cardiac enlargement, and rough systolic jet murmurs in the apical region and the 3rd and 4th intercostal spaces at the left sternal border. The disease has a global distribution and can be familial or sporadic, with more males than females in clinical cases and earlier and more severe symptoms in females. Most patients survive for decades. Of the deaths, 50% are sudden. Clinical manifestations 1, dyspnea; 2, strong apical pulsation and systolic rough jet murmur between the 3rd and 4th ribs at the left edge of the sternum. Diagnosis is based on 1. Non-obstructive type has fewer symptoms, with dyspnea in the early stage and atrial fibrillation and heart failure in the late stage. The obstructive type may have palpitations, shortness of breath, weakness after exertion, dizziness, syncope, angina pectoris and sudden death during activity.2. The heart border is enlarged to the lower left, and the apical part of the heart is pulsating with elevation. The non-obstructive type usually has no murmur, while the obstructive type often has a systolic jet murmur between the 3rd and 4th ribs at the left edge of the sternum.3. ECG: Left ventricular hypertrophy strain is common, and many patients have abnormal Q waves in the left thoracic leads and i and avl leads. Some patients have a combination of intraventricular conduction block or preexcitation syndrome.4. Echocardiography: septal thickness/rear wall thickness of the left ventricle is greater than 1 with abnormal forward motion of the anterior mitral leaflet during systole and narrowing of the left ventricular outflow tract.5. Left heart catheterization: there is a systolic pressure step difference between the left ventricular cavity and the left ventricular outflow tract in the obstructive type. Surgical treatment of refractory hypertrophic cardiomyopathy (Morrow surgery): About 3,000 obstructive patients in Europe and the United States underwent Morrow surgery, and the results of 40 years of follow-up proved that more than 95% of the obstructive cases underwent surgery had good results. Although it is not a curative method, the current expert consensus – surgery is the gold standard for the treatment of hypertrophic cardiomyopathy.