For the manifestation of calf edema, the first observation is from the surface. Generally, after the appearance of edema, wrinkles will disappear and the surface will be more shiny and may even be shiny. In addition, one may feel a sense of swelling. If there is an edema of the ankle face, one may feel that the shoes are small, and the squeezing feeling is more obvious when wearing shoes, and one may even be unable to put on shoes. If local pressure is applied, especially in the tibial plane, a more obvious indentation will appear, and this will prove the presence of calf edema. For calf edema, it often suggests some diseases, such as heart failure, which often results in calf edema. Then there are patients like those with renal insufficiency, especially uremia, which can cause water and sodium retention in the body, and this can cause edema in the limbs, which can lead to calf edema. In addition to the lower legs, facial edema will also be more obvious in patients with kidney failure. There are also some other diseases, such as hypoproteinemia, which will also cause edema, and edema in the calf area will also be more obvious.