Peripheral nerve entrapment, also known as nerve entrapment or peripheral nerve compression syndrome, is a group of signs of abnormal changes in nerve and vascular function caused by the compression of a peripheral nerve by scarring and adhesions of the surrounding tissues, especially bony prominences, bony fibrous tubular growths and masses. The disorder is more frequent in the limbs, more in the upper than in the lower limbs. Peripheral nerve entrapment is classified by the nature of Seddon’s nerve injury and falls into the first category – loss of nerve function – in which the main pathological change is demyelination of nerve fibers. After clinical release of the entrapped nerve, its function can rapidly improve or even return to normal within 1-2 days. This speed of recovery does not seem to explain the time and pattern required for the repair of demyelinated nerve changes. It has been suggested that the loss of nerve function caused by nerve entrapment is not always due to demyelination of nerve fibers, but rather is a mild injury due to altered electrolyte concentration and abnormal distribution of the embedded local nerve fibers, which does not produce organic changes. Thus, when the nerve entrapment is released, the nerve can be restored to function rapidly in a short period of time. Peripheral nerve entrapment syndrome can manifest clinically as a variety of disorders. Commonly, abnormal sensory femoral pain syndrome is a syndrome of abnormal sensation in the innervated area of the lateral femoral cutaneous nerve and pain in the anterolateral surface of the femur. (1895) was nominated by Roth as abnormal sensory femoral pain, so it is also known as Roth’s lateral femoral dermatomal neuritis. The syndrome is a common clinical condition. Etiology The lateral femoral cutaneous nerve emanates from the posterior roots of the lumbar 2 and 3 spinal nerves and is a sensory nerve. It passes from the lateral border of the psoas major muscle at the crest of the ilium, crosses the lower part of the iliofemoral membrane, reaches the anterior superior iliac spine and the inguinal ligament, and then descends at a right angle into the femur. From the inguinal ligament, it branches about 9 cm downward, with the anterior branch on the anterolateral surface of the femur to the knee and the posterior branch on the hip. If the nerve is compressed or injured in any part of its course, it can be the cause of morbidity. The former is mostly of unknown origin; the latter has more local factors, such as spinal diseases, abdominal and pelvic organ disorders, uterine compression in pregnancy, tight shorts, stiff waistbands and tight bandages that cause trauma, compression and stimulation in the groin. It is also believed to be related to systemic infection, wind and cold, and poisoning. Clinical manifestations Most commonly seen in middle-aged or older, obese men; those who prefer to wear tight shorts, women can also suffer from it. The ratio of men to women is 2.8:1, and people with leg trauma, diabetes, and pregnancy are more likely to develop the disease. The skin of the lower 2/3 of the anterior lateral femur has unilateral (occasionally bilateral) onset, with unexplained discomfort, numbness, tingling, burning, ankylosis, or searing pain. The pain is intermittent at first, but gradually becomes persistent, and is aggravated by prolonged standing or long-distance walking; rubbing of clothes; supine position; and overstretching of the thighs. In obese patients, local discomfort is most felt in sitting position. Clinical examination may reveal localized abnormalities in the lower 2/3 of the anterior lateral femur to the touch and even skin atrophy. In particular, there is often a limited pressure point directly below the anterior superior iliac spine (lateral femoral cutaneous nerve projection), with a radiating sensation to the distal extremity (positive Tinel’s sign). Tendon reflexes are present and muscle atrophy is not present. Treatment Etiological treatment: Remove the causative factors or carry out etiological treatment, such as avoiding the stimulation of various physical and chemical factors such as belts and tight pants, changing living habits, and correcting spinal deformities. Drug therapy Transcutaneous electrical stimulation therapy or physiotherapy Nerve block therapy Acupuncture therapy