Antiphospholipid syndrome is caused by the presence of antiphospholipid antibodies in a pregnant woman, and therefore, when she is pregnant with her second child, antiphospholipid syndrome can also occur. If a pregnant woman has antiphospholipid syndrome, it usually manifests as recurrent arterial or venous thrombosis, recurrent miscarriages and persistent positive anticardiolipin or lupus anticoagulation tests. If a woman has a need to continue the pregnancy, she needs to undergo regular labor and delivery tests during pregnancy and apply medications for symptomatic treatment under the guidance of a specialist. Aspirin can be taken as maintenance therapy during the preparatory stage of pregnancy. If pregnancy is confirmed, in order to avoid a poor prognosis, doctors usually recommend a combination of aspirin and low molecular heparin, which is the standard treatment regimen for the treatment of antiphospholipid syndrome in obstetrics. Therefore, if a woman has been diagnosed with antiphospholipid antibody syndrome, she will also be affected when she is pregnant with her second child, and it is recommended that she seek medical attention in time to take medication as directed by her doctor. If the pregnancy is confirmed, regular labor and delivery tests are required, and the medication regimen should be adjusted as prescribed by the doctor.