Many diabetic foot patients are left with large and deep wounds after cleaning, so is it possible to treat such wounds with skin or flap grafts? First, let’s understand the cause of diabetic foot. Poor long-term control of blood sugar in diabetic patients can cause blood atherosclerosis, vascular lesions contraction resulting in poor blood flow, inadequate supply of nutrients to local tissues, and reduced resistance to injury. The neuropathy makes the patient’s injury cannot be detected in time, and the high sugar level of the blood makes the injury site easy for bacterial growth and infection, plus the poor supply of nutrition to the foot. Next, let’s see how the skin grafting procedure is done. A skin graft is usually taken from healthy skin and used to cover the area after debridement, especially for large injuries that are commonly used to “heal” the wound quickly. I prefer to think that such a graft should be called a cosmetic procedure, a way to remove the east wall and repair the west wall. For patients with advanced diabetic foot with high blood sugar, the big risk of skin grafting is re-infection of the wound after surgery, which in reality is a big risk. Moreover, there are certain requirements for the patient to be able to implant the skin on the target wound, such as a scar or fresh granulation must be formed. But it is not easy enough for patients to reach this level, and doing surgery will cause secondary damage. Furthermore, the patient’s treatment is not everything will be fine once the skin is implanted! Because, diabetic foot patients’ lower limbs are mostly accompanied by neurological and vascular lesions, especially the local blood oxygen saturation of lower limbs does not go up, and there is no sufficient nutrient supply. Without solving these problems, the failure rate of implantation will increase. So, I do not advocate skin grafting, is there any way to promote wound healing and grow healthy tissues naturally? First of all, we must believe in the ability of our own cells to split and proliferate, and then one is the simmering pus to produce muscle in Chinese medicine theory. By the late stage of wound growth, Chinese herbal medicine high external application creates a wet environment for the wound to promote rapid proliferation of granulation tissue, which can naturally grow healthy muscle tissue after a period of treatment, and can avoid the damage caused by skin grafting to patients.