In general, for HBeAg-positive patients with chronic hepatitis, the indication for antiviral therapy is HBV DNA>20,000 IU/mL and persistent elevation of ALT (alanine aminotransferase) or evidence of fibrosis; for HBeAg-negative patients with chronic hepatitis, the indication for antiviral therapy is HBV DNA>2,000 IU/mL and persistent elevation of ALT or evidence of fibrosis. Evidence. In addition, according to the recommendations for the management of hepatitis B, all patients with cirrhosis should receive antiviral therapy as long as HBV DNA is detected, regardless of the ALT level. In patients with hepatitis B, the need for antiviral therapy should be decided by a specialist after assessment. Usually, they should avoid alcohol, quit smoking, avoid overwork, exercise properly, enhance physical fitness, supplement vitamins and proteins appropriately, and avoid excessive calorie intake and over-nutrition.