If a patient with gallstones has pain, it is important to determine whether the pain is caused by gallstones, because other diseases of biliary obstruction can also lead to abdominal pain, so pay attention to the identification and give different treatment measures.1. Clearly the pain caused by gallstones: the common pain of gallstones is located in the right upper abdomen, and some of the pain will radiate to the right shoulder and back, and also combined with discomfort such as anorexia, nausea, vomiting, abdominal distension The symptoms are caused by stone obstruction or inflammation, and fasting is required first. In case of stone obstruction, it can cause secondary bacterial infection, which needs to be treated with sensitive antibiotics such as cephalosporin, combined with anti-anaerobic drugs such as tinidazole. For patients with obvious abdominal pain symptoms, they can be treated with antispasmodic and analgesic drugs such as scopolamine, and should also receive surgical treatment such as laparoscopic cholecystectomy as soon as possible. 2. Pain caused by non-specified gallstones: If the pain manifests as biliary colic or spasm, the situation is more serious and strong pain medication is not recommended to prevent masking the condition. Prompt medical treatment is needed because gallbladder spasm and biliary colic caused by certain biliary obstruction can lead to increased pressure of the gallbladder. It also tends to lead to ischemic necrosis of the gallbladder, complicating purulent cholecystitis and even producing gangrene and perforation, which may require consideration of emergency surgical removal treatment.