Creatinine 200umol/L is about stage 3-5 of chronic kidney disease. Chronic kidney disease is staged according to glomerular filtration rate, which is divided into stages 1 to 5. The accuracy of assessing patients’ glomerular rate filtration based on creatinine value alone is greatly discounted, because creatinine value is affected by age, gender, weight, nutritional status and muscle activity. It is also not possible to assess a patient’s indication for dialysis based on creatinine history alone. Creatinine 200umol/L, at this time the patient is mainly to control blood pressure, reduce proteinuria, protect residual renal function, delay the progression of renal function, and avoid the application of nephrotoxic drugs. At present, the drugs to protect renal function and lower creatinine are Bailing capsule, Jinshui Bao capsule, Haikun kidney hi capsule, and urinary toxicity clear granules. If the patient has symptoms of uremia, heart failure, uncontrollable infection, general edema, and poor diuretic effect, dialysis treatment can be performed.