If a patient has an enlarged heart and heart failure, how long he or she will live depends on the severity of the condition and whether the patient is taking the relevant medications on time, combined with relevant lifestyle interventions. For patients with severe heart failure, the one-year survival rate is about 50%. If the patient has only mild heart failure and is taking the relevant secondary prevention medications on time, it is possible to live 5-10 years. Patients with an enlarged heart are advised to take medications to prevent further heart enlargement, for example, patients are advised to take medications like perindopril, spironolactone, and metoprolol. If necessary, it is recommended that patients can also take drugs such as Nocinto, whose main component is sakubatril valsartan, which is a relatively new clinical drug to prevent the progression of heart failure.