Many people have kidney disease but can not properly understand it, for example, I am nephrotic syndrome, and he is chronic nephritis, why the doctor told me my disease can be completely cured but easy to relapse, while he can only control, or even need lifelong drug maintenance, which requires you to understand the different characteristics of different diseases. Nephrotic syndrome is divided into primary and secondary, primary nephrotic syndrome pathology type for minor lesions, easy to control and also easy to relapse; if it is thylakoid hyperplasia or membrane proliferation, or membranous, or focal segmental sclerosis, equivalent to chronic nephritis, bad control, easy to recur, perhaps need drugs for lifelong maintenance. The pathology of chronic nephritis is more IgA nephropathy, most of the regular treatment of urine protein in 2?3 months to turn negative, while the occult blood persists for a long time, the pathology of classification in Lee’s grade 3 or more the vast majority of patients need low-dose hormone or immunosuppressant lifelong maintenance. For example, patient A has nephrotic syndrome, the pathology is minor lesions, the disease is controlled with sufficient hormone at the beginning, the urine protein turns negative in about 10 days, after the course of hormone reduction or about 2 years, the patient stops the drug, the disease relapses, and is treated with sufficient hormone again. patient B has focal segmental sclerosis of nephrotic syndrome, repeatedly takes hormone and immunosuppressant, the urine protein appears repeatedly. Therefore, nephropathy patients in the treatment process, if the initial resistance to kidney puncture examination in the treatment of 3 months after the urine protein is still positive or the condition has not improved, it is recommended that kidney puncture examination, to understand the type of pathology at the same time on the disease medication and prognosis can make a scientific judgment!