In psychiatric clinical practice, there are always many patients’ family members who ask this question: Can pregnant women take psychotropic drugs? According to the existing literature, there are cases of pregnant women taking psychotropic drugs resulting in a freak birth, but the number is very small, and there is no conclusive evidence to show that such a freak birth must be caused by taking psychotropic drugs. Nonetheless, physicians are reluctant to recklessly administer psychotropic drugs to women in their third trimester of pregnancy unless their condition warrants it, because it is difficult to be absolutely certain that the fetus in her womb and the newborn child born to her will not be affected in any way by the administration of psychotropic drugs to a pregnant woman in any month of her pregnancy, or in her imminent conception. The following guidelines are provided for women to use psychotropic drugs during pregnancy: 1. Benzodiazepine hypnotics: the general principle is to use them with caution, especially in the first 3 months of pregnancy, Valium, Librium and Mirtazapine should be avoided (there is a risk of fetal cardiovascular malformations and cleft lip), whereas lorazepam and temazepam should be safer; 2. Mood stabilizers (antimanic and antidepressant): in the 3 months prior to pregnancy, lithium should be avoided as much as possible. months should try to avoid the use of lithium salts (due to rare cardiovascular malformations) and fluoxetine, in the first 3 months of pregnancy, should avoid the use of valproate and carbamazepine (risk of neuromyelin defects); 3, antipsychotics Phenothiazine (such as chlorpromazine): used in women in pregnancy, generally speaking, is safe, and it does not cause monstrous fetuses nor spontaneous abortions, preterm labor, or an increased risk of stillbirths, whereas olanzapine and clozapine, on the other hand, appear to be safer. Finally, patients of childbearing age should be reminded that the most important precautionary measure should still be to avoid the use of psychotropic drugs as much as possible, and that the correct view of the dangers and safety of the use of psychotropic drugs in pregnancy is that, under close observation, drugs such as olanzapine and clozapine should be used as much as possible, if necessary.