How long bile duct cancer with metastasis and combined with pancreatic cancer can live is related to many factors, but generally the life expectancy is only a few months. Cholangiocarcinoma has a high degree of malignancy and a poor prognosis, which is mainly related to the clinical type, pathological characteristics and treatment methods. Most patients with cholangiocarcinoma die within 3 months after diagnosis if they do not undergo any surgery and drainage. Bile duct cancer with metastasis and combined with pancreatic cancer of higher malignant level has poor therapeutic consequences, and the general survival period is only a few months of life, which is also related to the patient’s physical condition and treatment. Usually, surgery cannot be given for this condition, and radiotherapy can be given to prolong life. How long one can live is also related to the patient’s physical condition, treatment method and drug resistance. After diagnosis of bile duct cancer and pancreatic cancer, timely treatment should be given in order to prolong the life time and improve the quality of patients’ survival.