Methods of relieving eyestrain include periocular massage, hot compresses on the eyes, looking into the distance, and the use of medication, etc. The specific treatment is related to the patient’s condition. If eye fatigue is caused by prolonged overuse of the eyes, patients can do periocular massage to relax the eye muscles, thereby relieving visual fatigue. Patients should also look into the distance, following the 20-20-20 principle, i.e., for every 20 minutes of eye use, take a 20-second break and look into the distance of 20 feet (about 600 meters). Patients with visual fatigue can also use localized hot compresses on the eyes to promote blood circulation in the eyes and improve eye discomfort, but hot compresses should be careful to avoid burns. Patients with obvious symptoms of visual fatigue can also use anti-fatigue eye drops as prescribed by their doctor, such as seven-leaf digitalis glycoside eye drops, to improve eye discomfort. In addition, patients should develop good eye habits and avoid eye fatigue. It is recommended that patients with obvious symptoms of visual fatigue should consult a doctor in time to assess their condition and follow the doctor’s instructions for treatment.