A large red bumps on the body and itchy, consider the following conditions: 1, urticaria: the disease can appear red wind clusters or edematous erythema, rash size varies, the shape varies, a little up, a little down, fade after no trace. It is mainly due to allergic factors, infectious factors or metabolic disorder factors. In the treatment, you can take oral fexofenadine hydrochloride tablets and olopatadine hydrochloride tablets, combined with oral compound glycopyrrolate capsules. If the condition is more serious, it can be changed to static injection of compound glycopyrrolate, and if necessary, immunosuppressive drugs such as compound betamethasone injection can be injected intramuscularly. 2. Erythema multiforme: this disease is caused by allergic factors or drug stimulation factors, and will appear edematous erythema, accompanied by itching, and can be taken orally with Epinastine hydrochloride capsule and topical application of Denide cream.