Sore calf muscles in the morning can be caused by the following reasons: first, cold, cold can lead to inflammation of the fascia of the calf, resulting in sore calf muscles after waking up in the morning after the symptoms, in the activities of a while after the symptoms can be improved, this time to early diagnosis of the checkup, early warmth, physical therapy; second, fatigue, due to the fatigue of the leg of the fascia or acute injury to the muscles, resulting in soreness of the calf muscles. Fourth, rheumatoid, rheumatoid can also involve the joints of the whole body as well as the fascia and muscles of the legs, resulting in soreness after waking up in the morning. In this case, blood tests as well as X-rays and MRIs of the legs should be taken for diagnosis and treatment.