The causes of spots on the face in the 50s include excessive pressure, improper use of cosmetics, excessive exposure to ultraviolet rays and female endocrine disorders. 1. Excessive pressure: due to work pressure, long time in a state of tension, insomnia, staying up late, lack of sleep, depression, sadness, anxiety, etc. may make the face grow spots. 2. Improper use of cosmetics: Too much make-up or improper use of cosmetics leads to lead and mercury poisoning, which may also cause spots on the face. 3. Excessive exposure to ultraviolet rays: sunlight, excessive exposure to ultraviolet rays and pollution of the environment are all possible causes of spots on the face. 4. Female endocrine disorders: when women suffer from endocrine disorders such as weak ovarian function and menstrual disorders, it may also cause spots on the face. There are many other factors that may cause spots on the face in the 50s, so one should go to the hospital in time to make clear the cause of the disease and make corresponding treatment.