I believe that no one is a stranger to colonoscopy, but the peri-colonoscopy preparation of elderly people is often overlooked. First of all, due to the deterioration of their body functions, elderly people usually have one kind of problem when taking laxatives. Second, the elderly are often accompanied by a variety of underlying diseases such as hypertension, diabetes, heart disease, etc., which seriously affect the successful completion of colonoscopy in the elderly. 1, psychological care elderly people with the increase in age, physiological functions gradually declined, the patient is unwell to consult, there are nervousness, fear, doubt and other psychological barriers, do not know much about the colonoscopy, so the nurse should be kind and amiable attitude, to introduce the patient’s condition and colonoscopy purposes, methods and intraoperative with precautions. Therefore, the nurse should be kind, introduce the patient’s condition and the purpose, method and intraoperative precautions of colonoscopy. 2, intestinal preparation intestinal cleanliness is very important, can clearly display the lesion, help the physician to determine the lesion, shorten the operation time, reduce the occurrence of complications. For chronic constipation, 2d before the examination add 2-3 tablets of fruit guide to enhance bowel movement. On the day of examination, polyethylene glycol 4000 electrolytes (and cool) with warm water 2000-2500ml is usually used to cleanse the intestine in 4-6 oral doses. The final discharge of nearly clear water-like stool is sufficient. Closely observe the patient’s abdominal pain, abdominal distension, vomiting and other conditions to prevent inducing intestinal bleeding and acute intestinal obstruction and other complications. 3.Intraoperative care Focus on observing the patient’s vital signs, routinely give cardiac monitoring and blood pressure, heart rate, oxygen saturation monitoring, continuous oxygen 4~5L/min, establish intravenous access. The patient should lie on the left side with legs flexed, patiently explain to the patient the slight discomfort caused during the examination and operation, inform the patient of the precautions and methods of cooperation, and the nurse should consider the thin intestinal wall of the elderly when inserting the mirror. Avoid damage to the mucosa bleeding or perforation, and keep abdominal pain informed; colonoscopy is done by a doctor and nurse with the cooperation of two people, and careful observation is made when withdrawing the mirror to try to extract gas in sections to reduce abdominal distension and pain. During the operation, we pay attention to observe and ask patients about their feelings at any time, and no complications occurred in any case. 4, postoperative care After the colonoscopy, let the patient rest in bed and fast temporarily. A few patients may have slight abdominal distension and vague abdominal pain, so encourage patients to ventilate and defecate. For those who take pathological tissue biopsy, abdominal pain and blood in stool should be closely observed. If there is persistent abdominal pain and distension or bloody stool, the possibility of intestinal perforation or bleeding should be considered, and the physician should be notified immediately to check the patient and make judgment and reasoning. In conclusion, elderly patients can generally tolerate colonoscopy, but special attention should be paid to the elderly over 70 years of age to master the indications and contraindications. The operating colonoscopist should be technically proficient; clean the intestine well, shorten the operation time; intraoperative blood oxygen cardiac monitoring, careful operation, and close postoperative observation of the condition, generally can safely and successfully complete the examination and clear diagnosis.