As the saying goes, “When the cauliflower is yellow, the madman goes mad”. Although there is still some time before the cauliflower is yellow, this phenomenon has already appeared in the outpatient clinics of the psychiatry and psychology departments of our hospital. The number of people attending the clinic has risen significantly. Spring is the season of high incidence of mental illnesses, due to the spring sunshine and temperature changes, affecting the human body’s internal biological secretion and emotional changes, catecholamines and 5-hydroxytryptamine two neurotransmitters in the human brain play a role in regulating the function of emotions, the dramatic changes in the spring weather, will make the two nerve mediators of the content of the decline, which leads to greater personal mood fluctuations, prone to impulsivity, irritability and other bad moods, especially to the Schizophrenia and bipolar disorder, two relatively serious mental illnesses with high recurrence. In addition to climate-related, mental illness in the spring also has multiple reasons, on the one hand, the spring is the beginning of the year, this time everyone is facing a lot of new tasks, new jobs, new pressures, life is more monotonous or introverted, lower psychological quality of the people in this season is more prone to morbidity, prone to depression, anxiety and other psychiatric symptoms. In addition, the family members of people with a history of mental illness should pay attention to this time, for psychiatric patients, the most important thing is to adhere to the medication, regular follow-up. Prevention of relapse of mental illness can start from several aspects: First, the mental patient is best to carry out certain activities, if the condition is more stable, it is best to participate in some simple work, so that they have some social activities, but should not be engaged in heavy, stay up late at work, adhere to the normal work and rest shall prevail. Secondly, they should live a regular life, go to bed early and get up early, have moderate activities, and stretch their body and mind. Third, a balanced diet, should not be too late to complement the food, such as ginseng, antler belongs to the big complementary food should not be eaten, a variety of carbonated beverages should not be drinking, especially can not drink alcohol.