Lung nodules do not necessarily disappear after quitting smoking. Lung nodules are divided into benign lesions and malignant lesions, if the patient is subjected to bacterial infection, caused by local inflammatory stimulation caused by benign lung nodules, the lesion is relatively small, after quitting smoking, timely use of antibiotics such as amoxicillin, levofloxacin, etc. for treatment, lung nodules may disappear. If the lung nodules are relatively large, especially if malignant lung nodules are present, even after smoking cessation, it is not very likely that the lung nodules will disappear, and there may be a continuous aggravation of the disease. When patients develop lung nodules, they need to be examined for tumor markers and, if necessary, undergo puncture for pathological biopsy, which can clarify whether the lesion is benign or malignant. According to the examination results, appropriate treatment can improve the patient’s condition as soon as possible.