Drugs that have been shown to induce or exacerbate psoriasis include: 1. beta-blockers: Takayasu (propranolol), apranolol, etc.; 2. non-steroidal anti-inflammatory drugs: anandamide, pautazone, ibuprofen, diclofenac, etc.; 3. calcium antagonists and angiotensinase conversion inhibitors: nifedipine, nimodipine, nicardipine, etc.; 4. antimalarials: hydroxychloroquine; 5. immunomodulators. Interferon, thymidine, etc. Because immunomodulators such as interferon and thymidine can induce the production of cytokines such as IFN-α and IFN-γ, which may induce and aggravate psoriasis, doctors must carefully understand their immunomodulatory mechanisms before prescribing them.