Long-term running will have a certain effect on lowering blood pressure, but can not effectively control the level of blood pressure, patients with high blood pressure should be regular oral drug treatment. It is very important for patients with hypertension to make adjustments to their lifestyles, such as adhering to physical exercise. Adherence to physical exercise can have a certain effect on the reduction of blood pressure levels, is an important auxiliary way of hypertension treatment, but running is not stable effect of lowering blood pressure, can not be used as the main way of lowering blood pressure. Patients with high blood pressure should be treated with regular oral medication, and the effect of medication in controlling blood pressure is relatively clear. Antihypertensive drugs are mainly divided into five categories, such as calcium antagonist felodipine, β-blocker metoprolol, angiotensin-converting enzyme inhibitor captopril, angiotensin II receptor antagonist timosartan, and diuretic spironolactone. Running is beneficial for hypertensive patients, usually pay attention to adhere to, but also under the guidance of the physician’s formal oral medication.