The drugs for varicose veins are divided into the following three categories. 1. drugs that promote venous reflux: these drugs can help patients promote venous reflux, reduce vascular permeability, lower venous hypertension, and relieve the symptoms of varicose veins. The main representative drugs are mazerin, vilastatin, calcium hydroxybenzene sulfonate, diosmin, etc. 2, anticoagulant drugs: these drugs are generally used in patients with combined varicose veins thrombosis. If varicose veins form superficial venous thrombosis and the thrombosis is close to the opening of femoral vein, it is recommended to use anticoagulant drugs for symptomatic anticoagulation and dissolution of thrombosis. Common anticoagulant drugs are warfarin, low molecular heparin, rivaroxaban, dabigatran, etc. 3, topical varicose veins drugs: varicose veins form itching, flaking and other dermatitis changes, can be used to relieve symptoms with topical drugs such as Xizitol, Bactrim.