Melanoma can be treated with interferon, but this is only an adjuvant treatment, the main treatment is still surgery. Melanoma is a tumor caused by malignant transformation of melanocytes, with a high degree of malignancy, and the main treatment is surgery. For early stage patients, it is recommended to resect the primary lesion and decide the scope of surgery according to the depth of infiltration. For advanced patients, in addition to surgical resection, regional lymph node dissection should be done. After surgery, interferon can be used for adjuvant treatment to improve the immunity of patients and stop the replication of virus in virus-infected cells. Interferon may have some adverse reactions, such as fever, erythema at the injection site, hair loss, rash, etc. It is contraindicated if you are allergic to this drug, if you have severe cardiac, hepatic or renal insufficiency, and if you have bone marrow suppression. If you need to use the drug, it is recommended to use the drug under the guidance of a doctor, not blindly self-medication to avoid adverse effects.