Many patients refuse peritoneal dialysis because they say they do not have sterile conditions at home, but the requirement for a dialysis room environment is not the presence or absence of that sterile room, but whether the patient has a concept of sterility. An operator with an aseptic mindset will be very skillful in turning a space into a room suitable for peritoneal dialysis operations. In principle the room should preferably be a single room, or a room with low turnover of people, for example, a patient’s bedroom or a single office can become a peritoneal dialysis operating room. The number of furniture in the room should be minimized, and the outer surface of the furniture should be easy to disinfect and wipe, and avoid placing too high cabinets, the top of which is easy to accumulate dust and cause floating pollution. The room should minimize the decorations and various ornaments and other items that are not easy to clean. The room should be clean, dry, ventilated (windows), well-lit, and there should be no sewers or vents. Vents and drains are easy places for cockroaches, rats, flies, etc. These pests can contaminate the operating room by crawling around. Before each dialysis, the operating room should be cleaned by opening the windows for 10 minutes, closing the room and then wiping the floor and countertop with chlorine-containing disinfectant, and then irradiating the UV lamp for 40 minutes (2 times in the morning and evening is sufficient). After cleaning the operating room, the complete operation of peritoneal dialysis fluid exchange should be performed immediately, and the windows can be opened and ventilated again after completion to reduce the odor from the disinfectant and UV lamp. If available, patients can establish their own dedicated peritoneal dialysis operating room in their bedroom or balcony. The outside is divided by a glass partition to create a small room of about 2O, in which only the operating table, UV lamp, chairs, shelves for hanging liquids, clocks, and various items are placed. Avoid frequent entry and exit of personnel other than the patient and the operator, and change special shoes when entering. Some patients who have travel and tourism requirements can also make simple preparations in the hotel by finding a suitable room according to the above requirements, ventilating and disinfecting the room with their own chlorine-containing disinfectant solution (there are commercially available chlorine-containing tablets that can be dissolved in water, such as Kinzin), spraying and wiping the operation area, and then performing a complete fluid exchange operation. Of course, it is best if one can contact the local abdominal dialysis center in advance and borrow their operating room for fluid exchange.