The life expectancy of patients with amyotrophic lateral sclerosis is usually about 5 years after diagnosis, and a few patients may live more than 10 years. Amyotrophic lateral sclerosis is one of the most common types of motor neuron disease. It is characterized by damage to both upper and lower motor neurons, starting with muscle atrophy in the distal part of both upper limbs, and then gradually expanding to cover the whole body with muscle atrophy and muscle weakness, and ultimately the pharyngeal and respiratory muscles are involved, resulting in the inability of the patient to swallow and breathe, and the patient needs to use a gastric tube and nasal feeding to maintain life, and a ventilator to assist ventilation and ventilation. The patient needs to be fed nasally through a gastrostomy tube and ventilated with a ventilator to maintain ventilation and air exchange. After the patient’s condition progressively worsens, most patients die in about 5 years due to respiratory failure caused by respiratory muscle paralysis or severe lung infections, but if the patient is treated in time and maintained well on a ventilator, life expectancy may be extended to more than 10 years.