It is possible to cure neuroblastoma in advanced stage. In terms of treatment, after clear diagnosis, certain degree of chemotherapy will be given first, and after the tumor shrinks, surgery and subsequent chemotherapy will be administered according to the specific situation. If the metastatic location can be completely eliminated, such as lung or skin metastasis or bone marrow metastasis, after surgery, chemotherapy, radiotherapy, bone marrow suppression and even immunotherapy, the metastatic lesions and the primary lesions can be completely eliminated, and there is a possibility of cure, with a ratio of 20%-30%. With the development of medicine, the treatment effect of advanced neuroblastoma is getting better and better, so parents should not be too desperate. If there are metastases in some locations that cannot be removed, such as intracranial metastases or ocular metastases, after the primary lesions are surgically removed, the metastases cannot be removed, and the treatment measures such as radiotherapy cannot completely disappear or relieve the disease, so there is no way to achieve a complete cure.