There are many symptoms of intrahepatic bile duct stones, and many patients have right upper abdominal pain with fever, which is one of the symptoms (more often). It is necessary to know the symptoms of intrahepatic bile duct stones in order to know the intrahepatic bile duct stones early and treat them early. What are the symptoms of intrahepatic bile duct stones? The symptoms of intrahepatic bile duct stones are mainly right upper abdominal pain with fever. In some patients, there is no biliary infection in the early stage, only mild epigastric discomfort, but in the later stage, biliary cirrhosis, liver atrophy, liver abscess and other serious complications may occur. The biliary cirrhosis, liver atrophy, liver abscess and other serious complications may occur. Periodic intermittent attacks are the characteristic clinical manifestations of intrahepatic bile duct stones. During the interval of the disease, there are usually no symptoms or slight discomfort in the epigastrium; however, in the acute phase, symptoms of acute septic cholangitis or Charcot’s triad of varying severity may appear, mostly caused by combined extrahepatic bile duct stones. In patients without combined extrahepatic bile duct stones, intrahepatic bile duct stones in one side or one lobe may cause obstruction of the intrahepatic bile ducts in one half of the liver or one segment of the liver. When secondary infection occurs, symptoms of systemic infection such as chills, fever, and sometimes even psychiatric symptoms and shock may occur in acute severe cholangitis, still without obvious abdominal pain and jaundice.