Tremors of the tongue are usually seen in patients with Parkinson’s disease and are a symptom of damage to the nervous system. It may also be caused by damage to the brain nerves, or it may be caused by stimulation of the brain nerves due to long-term drug use. It manifests as a slow rhythmic tremor, with 4 to 6 tremors per second, with variable amplitude, and increases with stress. Many patients also have postural tremors of 5 to 8 times per second. Parkinson’s disease, commonly known as Alzheimer’s disease, is a progressive brain disease caused by the destruction of cells in the brain that control movement. The loss of cells in the brain that make the enzyme dopamine is the main cause of Parkinson’s disease, and once the loss reaches 80 percent, symptoms may begin to appear. Diagnostic criteria for Parkinson’s disease: 1. A decrease in hypervanillic acid in the cerebrospinal fluid is helpful in confirming the diagnosis of early Parkinson’s disease and in differentiating idiopathic tremor and drug-related Parkinson’s syndrome from Parkinson’s disease. In general, idiopathic tremor is sometimes easy to differentiate from early primary Parkinson’s disease. Idiopathic tremor is characterized by positional and motor tremor of the hands and head without hypokinesia and hypertonia. 2, the diagnosis of Parkinson’s disease depends on the presence of atypical symptoms and signs that do not support the diagnosis of primary Parkinson’s disease. For example, cone bundle signs, disuse gait disorder, cerebellar symptoms, intentional tremor, gaze palsy, severe vegetative dysfunction, and significant dementia with mild extrapyramidal symptoms.