Q: Hello, Professor Tong! I have the following confusion about hepatitis B treatment, and I would like to thank you for your time to answer it. 1.Some people say that enzyme-lowering and liver-protecting drugs achieve their goal by breaking down transaminases in the blood and reinforcing hepatocyte membranes, if so, enzyme-lowering treatment is only a method to treat the symptoms, and whether it is meaningful for hepatitis B treatment. 2, transaminases are elevated as a result of the body’s clearance of hepatocyte virus, so whether lowering enzymes to protect the liver will prevent the body from clearing the virus. 3.Does the body have to destroy the liver cells to clear the virus, and will the transaminases necessarily rise. 4.Whether liver fibrosis is reversible. 5, I tend to use pure Chinese medicine to treat, whether there are cases of Chinese medicine curing viral hepatitis. A: Your question is very professional, the answer is as follows: 1, the liver anti-inflammatory therapy drugs are divided into five categories, different drugs have different points of action, including anti-inflammatory and stabilization of hepatocyte membrane, antioxidant, to prevent liver cell damage. The purpose of hepatoprotection is to prevent and reduce as well as repair hepatocyte damage, thus preventing excessive liver damage and thus stopping the progression of liver fibrosis, and thus still has a certain status in clinical treatment. 2. Patients in the clearance phase have elevated ALT, when the host immunity leads to the clearance of the virus, with the elevation of ALT, the virus decreases, but it is difficult for the organism to clear the virus at once, repeated clearance is needed, according to my study, 17% of patients can clear the virus by themselves, but the median clearance time takes more than 4 years, thus, such repeated liver damage, easily leads to liver fibrosis and thus cirrhosis, so our study of patients who have not The study of patients who underwent antiviral therapy found that after hepatoprotective therapy, the body cleared the virus spontaneously and the incidence of cirrhosis was significantly lower than that of patients who did not undergo hepatoprotective anti-inflammatory therapy. The current clinical study concluded that antiviral therapy is effective when ALT is elevated, because this is when the body’s antiviral immunity is enhanced and the therapeutic effect is easily achieved, but antiviral combined with hepatoprotective therapy can reduce liver injury, and there is no evidence that it affects the antiviral effect, but instead reduces the development of inflammation and rapidly reduces fibrosis or accelerates its reversal. 3, the body has two ways to clear the virus, one is through lysis of cells, one is not through lysis of cells. If the body’s cytokines such as interferon, tumor necrosis factor, often not through lysis to remove extracellular and intracellular viruses. That is, some patients do not appear ALT elevation, and the virus is cleared and become inactive carriers. 4, not only liver fibrosis can be reversed, even cirrhosis can be reversed, so the European and American societies have now redefined cirrhosis. 5.The national eleventh and twelfth five-year major projects we have undertaken all use pure Chinese medicine to treat hepatitis B patients, and some patients can achieve, after up to two years of Chinese medicine treatment, to become inactive carriers, and if there are recurrent liver function abnormalities, antiviral treatment can rapidly suppress the virus and prevent cirrhosis from occurring. Thus, clinical treatment needs to be evaluated to select the best treatment plan to maximize patient benefit.