Hyperlipidemia (dyslipidemia)

  The composition of blood lipids. Lipids are the general term for the lipids contained in the blood, which mainly include cholesterol and triglycerides, in addition to phospholipids, glycolipids, steroids and free fatty acids. Lipids play an important role in maintaining normal physiological activities in the body. Most of the triglycerides are obtained from the diet, and a small portion is synthesized by the body itself, mainly involved in the body’s energy metabolism. Cholesterol is mostly synthesized by the body itself, with a small portion obtained from the diet, and plays a key role in stabilizing the normal function of cell membranes.  There are light and heavy lipoproteins in the blood. The denser, smaller particle fraction is called HDL, which transports excess cholesterol from the walls of blood vessels back to the liver for metabolism and is known as the scavenger of blood vessels. HDL and the cholesterol it carries are the “good cholesterol” with anti-atherosclerotic properties. On the contrary, LDL carries cholesterol from the liver to the peripheral blood vessels, especially to the coronary arteries in the heart, which can cause excessive cholesterol to accumulate on the walls of the blood vessels and cause atherosclerosis, therefore, LDL and the cholesterol it carries are “bad cholesterol”. In short, LDL is better when it is low and HDL is better when it is high.  What is hyperlipidemia. Dyslipidemia, commonly known as hyperlipidemia, is a condition in which the level of one or more lipids in the body’s plasma exceeds the normal range due to abnormal fat metabolism, including high total cholesterol, LDL cholesterol and triglycerides, or low HDL cholesterol, so the common name “hyperlipidemia” is not entirely appropriate. The number of people suffering from dyslipidemia is about 160 million nationwide. Dyslipidemia is insidious, progressive and systemic, often lacking obvious clinical symptoms, and is mostly detected during physical examinations. There are many causes of dyslipidemia. Excessive production and/or reduced clearance of lipids from any cause can lead to accumulation (or reduction) of one or more lipid fractions in the plasma.  Clinical classification of dyslipidemia. Clinical classification is usually divided into two categories: primary and secondary dyslipidemia. Those due to genetic defects are referred to as primary dyslipidemia, also known as primary familial dyslipidemia, and non-familial dyslipidemia, also known as sporadic dyslipidemia. Those due to systemic diseases are called secondary dyslipidemia.  The dangers of hyperlipidemia. Hyperlipidemia is a high-risk factor for many cardiovascular diseases such as coronary heart disease, angina pectoris and hypertension, and its immediate danger is to accelerate the process of systemic atherosclerosis. This can lead to a series of vascular-related complications, such as angina, myocardial infarction, arrhythmia and other cardiovascular diseases, or cerebrovascular diseases such as cerebral infarction and cerebral ischemia, and can also lead to nephropathy and gangrene of the upper and lower limbs, which can cause disability or even death and seriously affect the quality of life and life safety. In short, hyperlipidemia is the pathophysiological basis of cardiovascular diseases and is a silent killer of health.  Adjustment and treatment of hyperlipidemia: (1) Pay attention to scientific diet and control food lipid sources. Common lipid-lowering foods are: soybean: contains eight essential amino acids, a variety of vitamins and trace elements, can reduce the blood cholesterol. Peanuts: peanut oil helps to break down cholesterol in the liver and lower blood cholesterol. Mushroom: contains a purine derivative, which has a significant hypolipidemic effect. Garlic: Contains volatile chorine, which can remove the fat accumulated in blood vessels and has a significant cholesterol-lowering effect. Onion: Contains triallyl disulfide and sulfur amino acids, which have good hypolipidemic effects. Ginger: Contains oleoresin. It can inhibit the absorption of cholesterol by the body. Tea: has a significant cholesterol-lowering effect. Honey orange: accelerates the transformation of cholesterol and reduces cholesterol and blood lipid content. Yogurt: Significant cholesterol-lowering effect. In addition, snapper, corn oil, sunflower seeds and seaweed all have cholesterol-lowering effects.  (2) Strengthen sports and promote body metabolism. A large number of clinical studies have shown that strengthening exercise promotes the transfer, decomposition and excretion of lipids in the blood, regulates glucose metabolism and reduces blood viscosity, which shows that exercise plays an important role in the treatment of hyperlipidemia. Patients with hyperlipidemia can participate in some sports, such as jogging, tai chi, walking, swimming and other activities according to their needs.  (3) Selective medication regulation for lipid levels to reach the standard. In the case that the above two ways of cooperation, but still can not achieve the desired effect, to consider the drug regulation. Commonly used drugs include: lowering plasma cholesterol mainly: abbreviated cholesterol, cholinesterase, elastase, etc.; lowering cholesterol and triglycerides at the same time: statins mainly, including lovastatin, simvastatin, atorvastatin, etc.; lowering plasma triglycerides mainly, common ones are, niacin, clofibrate, benzofibrate, yidolipid, etc.