Melasma is a yellowish brown or dark brown patch on the face of young and middle-aged women, usually symmetrically distributed on the cheek, cheek, butterfly-shaped or irregular-shaped, and is the culprit affecting women’s facial appearance. There are many causes of melasma, including sunlight, oral contraceptives, cosmetics, pregnancy, endocrine and heredity. There is no effective treatment for melasma, which is a major problem in the treatment of pigmentation diseases. However, it is not that there is no medicine to cure or no solution. To treat melasma, we should actively search for the causative factors and deal with them accordingly. According to the depth of melanin of melasma, it can be divided into epidermal type and dermal type. The effect of phototherapy is more ideal for epidermal melasma. After treatment, strict sun protection and daily topical application of L-Vc should be applied, and the effect is still ideal. The effect of any single treatment for dermal epidermal melasma is not good, and a comprehensive treatment plan should be adopted: for example, add L-Vc import after phototherapy, and use L-Vc in the morning and evening in daily life to insist on about half a year to gradually make it fade; you can also cooperate with fractional laser treatment for melasma, and pour in L-Vc after the scabs fall off in fractional treatment, once or twice a week, and pay attention to sun protection daily, the effect is still good. The treatment of melasma should not be rushed, the desire for speed is not achieved.