Anti-cardiolipin antibody can destroy cell function, resulting in hypercoagulability of blood, hemolytic anemia and other manifestations. Positive antibody can be seen in autoimmune diseases such as systemic lupus erythematosus, antiphospholipid syndrome, and viral or mycoplasma infections. Therefore, different treatments should be taken according to the cause of the disease to turn anticardiolipin antibody negative.
1. Patients with systemic lupus erythematosus have a high detection rate of this antibody, which is closely related to neurological thrombosis. While applying anticoagulation drugs such as heparin and warfarin, patients should add glucocorticosteroids such as prednisone, immunosuppressants such as leflunomide or cyclophosphamide to control the condition. Through effective treatment, some patients’ antibodies can become negative.
2. Patients with antiphospholipid syndrome, characterized by positive antibody, may have recurrent arteriovenous thrombosis and habitual abortion. Usually, anticoagulation such as warfarin can effectively control the condition, and some more serious patients can be treated with glucocorticosteroids such as prednisone, combined with immunosuppressive agents such as hydroxychloroquine, and the antibody of some patients can be turned negative.
3. In addition, some patients with viral infections may also have positive anticardiolipin antibodies, such as chickenpox, rubella virus, and mycoplasma infections. These patients can be treated with antiviral drugs such as acyclovir or azithromycin for mycoplasma infections, and the anticardiolipin antibodies can be turned negative after the symptoms are effectively controlled.
Patients with positive anticardiolipin antibodies are advised to go to the rheumatology and immunology department of the hospital as soon as possible to clarify the cause of the disease, and to carry out standardized treatment under the guidance of the doctor, so as to avoid delaying the condition.