Treatment of pleural fluid

　　In the past, it was believed that pleural fluid was a sign of advanced lung cancer and an absolute contraindication to cesarean surgery. Pleural fluid can cause symptoms such as dyspnea, cough and chest pain, which are even more harmful to patients than lung cancer itself. Therefore, the treatment of pleural fluid is a difficult problem in lung cancer treatment.　　The cancer tumor of lung cancer patients gradually increases and compresses the lung and dirty pleura before invading the chest wall tissues, which affects the reabsorption of fluid and protein, and the fluid in the pleural cavity accumulates to form pleural fluid. At this time, although pleural fluid appears, there is no metastasis of cancer cells on the chest wall. If the general condition is good and there are no contralateral lymph nodes or distant metastasis, there is still hope to achieve the purpose of radical cure through surgery. If not treated in time, pleural fluid not only produces serious clinical symptoms, but also tumor will easily metastasize to the wall pleura soon. Therefore, at present, pleural fluid is no longer a sign of advanced stage of lung cancer. For patients with lung cancer with pleural fluid, surgical removal of the lung lobe affected by the tumor, together with reasonable treatment after surgery, can achieve better results.　　For patients who are really inoperable, it is very important to eliminate the pleural fluid and relieve the symptoms. After thoracentesis to release fluid, chemotherapeutic drugs and sclerosing agents can be injected into the chest cavity to cause adhesions in the chest cavity and eliminate the potential cavity where the pleural fluid is retained. Drug sensitivity testing of tumor cells in pleural fluid can help doctors understand the sensitivity of tumors to different chemotherapeutic drugs, allowing for more targeted treatment in the future. More than half of the malignant pleural fluid in patients with advanced lung cancer can be relieved with lymphocytes obtained from pleural fluid culture and reinjected into the pleural cavity.