1, the effect of pregnancy on hepatitis B: pregnancy can make patients with hepatitis E liver failure or hemorrhage, there is a high mortality rate; and acute hepatitis B, seems to have no significant effect, but if it occurs at the end of pregnancy, must be glanced at, kicks cause fulminant hepatitis B. Pregnancy on AsC, only individual reports can cause lesion activity; mild chronic hepatitis B patients such as multiple pregnancies, may aggravate the disease. Patients with more severe chronic hepatitis B or active cirrhosis often have amenorrhea and hypogonadism and rarely become pregnant; pregnancy, if any, may worsen hepatitis. May be due to increased plasma volume and cardiac output, increased intra-abdominal pressure, cirrhotic pregnant women are more likely to have upper gastrointestinal bleeding. 2, the effect of hepatitis B on pregnancy: European and American countries reported that hepatitis has no effect on pregnancy except for the high rate of preterm labor, and the survival rate of preterm babies depends on the degree of maturity at the time of delivery, which is directly related to the mother’s condition. Domestic reports vary, with 20-30% of early and midterm pregnancies causing miscarriage; acute hepatitis B occurring at the end of pregnancy may cause preterm labor, stillbirth and neonatal asphyxia. Even in HBEAG(+) mothers, breastfeeding transmission is very unlikely as long as the nipple is not bitten. The effect of chronic hepatitis B or cirrhosis on pregnancy varies from case to case: if the active hepatitis has subsided and the cirrhosis is well compensated, there may be no significant obstruction; otherwise it may also cause preterm labor, stillbirth, or neonatal asphyxia. The pathology of hepatitis B-associated cirrhosis seldom leads to pregnancy in women, and pregnancy does not appear to have a significant effect if the lesions are quiescent.